A randomised crossover trial of a new, rapid method of detecting methicillin-resistant Staphylococcus aureus (MRSA) and comparing against conventional screening: in terms of the efficacy and the effect upon hospital methicillin-resistant Staphylococcus aureus infection rates, transmission rates and the use of hospital resources

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN75590122

Enrollment

15000

Registered

2006-01-10

Start date

2006-01-01

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

MRSA colonisation (infection and bacteraemia) Infections and Infestations Bacterial infection of unspecified site

Interventions

The use of a rapid method in detecting MRSA. This will be compared against the currently employed non-rapid method of detection.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: All patients admitted to 10 study wards in the duration of the study.

Exclusion criteria

Exclusion criteria: Patients not wishing to participate in the study.

Design outcomes

Primary

Measure	Time frame
Ward MRSA transmission rates.	—

Secondary

Measure	Time frame
1. Ward MRSA bacteraemia rates 2. Ward MRSA clinical infection rates 3. Length of hospital stay 4. Use of isolation facilities 5. MRSA-related nursing workload 6. Rapid test sensitivity, specificity, positive predictive value, negative predictive value, turn around time and cost with the conventional method using screening swabs taken under routine conditions 7. Economic analysis	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Apr 5, 2026