Do mentalisation-based interventions work for patients with borderline personality disorder and chronic depression?

Effectiveness of mentalisation-based interventions and their influence on the therapeutic alliance for patients with borderline personality disorder and chronic depression: a single case study of three psychoanalytic long-term therapies based on the plan formulation method (Control Mastery Theory)

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ISRCTN

Registry ID

ISRCTN75536830

Enrollment

Registered

2009-09-08

Start date

2009-09-01

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Major depression recurrent, dysthymia, borderline Mental and Behavioural Disorders Recurrent depressive disorder

Interventions

Specific interventions are studied in an observational trial. Due to psychodynamic/psychoanalytic treatment, it is not possible to control the interventions actively without distortion of the therapeu

TI: therapist intervention

P2: patient remark 2) 2.1. Two raters will rate sections P1-TI for pro-plan/anti-plan and two raters will rate sections P1-TI for mentalisation promotion 2.2. Two raters will rate each section P1 and

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients with a psychoanalytic treatment longer than 100 sessions 2. Aged 18 - 60 years, either sex 3. Diagnosis: major depression recurrent (DSM 296.3) or dysthymia (DSM 300.40) or borderline (DSM 301.83). Diagnosis Diagnostic and Statistical Manual of Mental Disorders, fourth edition (DSM-IV) proved by an independent interviewer with the semi-structured interview Structured Clinical Interview for DSM-IV (SCID) I and II.

Exclusion criteria

Exclusion criteria: 1. Psychosis 2. Drug or alcohol addiction 3. Organic brain diseases

Design outcomes

Primary

Measure	Time frame
1. Therapists Interventions (pro-plan, mentalisation promotion) and Experiencing Scale: assessment by trained clinical experts in 5-minute sections and in identified episodes 2. Therapeutic Alliance-Revised (STA-R) and The Bern post session reports: assessment by the patient after each session within the special intervals (sessions 0 - 10, 20 - 30, 50 - 60 and 90 - 100)	—

Secondary

Measure	Time frame
1. Symptom Check List (SCL-90-R) and Interpersonal Problems (IIP): assessment by the patient at the beginning and end of each special interval, at the end of the therapy and 1 year follow up 2. Beck Depression Inventory (BDI) and Borderline Personality Inventory (BPI): assessment by the patient at the beginning and the end of the therapy and 1 year follow up	—

Countries

Germany

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026