Survey of the current management of secondary hyperparathyroidism (SHPT) in patients with end-stage renal disease undergoing dialysis in the UK NHS

A cross-sectional survey of the current management of secondary hyperparathyroidism in patients with end-stage renal disease undergoing dialysis in the UK NHS

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ISRCTN

Registry ID

ISRCTN75383472

Enrollment

3000

Registered

2013-12-11

Start date

2011-06-06

Completion date

Unknown

Last updated

2022-04-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Secondary hyperparathyroidism Nutritional, Metabolic, Endocrine Secondary hyperparathyroidism, not elsewhere classified

Interventions

Data regarding renal unit service structure and local policies relating to SHPT management were obtained through review of written Trust/department policies and staff complement /staffing structure/or

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients undergoing haemodialysis or peritoneal dialysis with a PTH greater than 15pMol for at least one reading in the 12 months prior to the data collection period. 2. Patients with a PTH 15pMol or less who have been prescribed a phosphate binder within the 12 months prior to the data collection period.

Exclusion criteria

Exclusion criteria: Patients undergoing dialysis for less than 90 days prior to the data collection period.

Design outcomes

Primary

Measure	Time frame
As of 31/10/2017: % patients with all stipulated biochemical markers within target range according to: • UK Renal Association Clinical Guidelines • KDOQI Guidelines • KDIGO Clinical Practice Guideline Prior to 31/10/2017: N/A - observational study	—

Secondary

Measure	Time frame
As of 31/10/2017: % patients with all stipulated biochemical markers within 25%, 50%, 100% of target range, and more than 100% outside target range, according to: • UK Renal Association Clinical Guidelines • KDOQI Guidelines • KDIGO Clinical Practice Guideline % patients with all stipulated biochemical markers within target range at date of data collection and at 3 months prior to data collection according to: • UK Renal Association Clinical Guidelines, • KDOQI Guidelines, • KDIGO Clinical Practice Guideline Achievement of UK Renal Association Guideline targets (single, dual) Achievement of KDOQI Guideline targets (single, dual, triple) Achievement of KDIGO Guidelines targets (single, dual) Description of services and policies related to SHPT management: • Number of whole time equivalent consultant renal physicians per 100 dialysis patients • Number of whole time equivalent junior doctors per 100 dialysis patients • Number of whole time equivalent dietitians per 100 dialysis patients • Number of whole time equivalent bone disease specialist nurses per 100 dialysis patients • Number of whole time equivalent renal pharmacists per 100 dialysis patients • Number of whole time equivalent surgeons who conduct parathyroidectomies per 100 dialysis patients • Hospital guidelines used to shape clinical practice • Hospital policy regarding availability of cinacalcet • Hospital policy regarding availability of non-calcium containing phosphate binder • Hospital policy regarding parathyroidectomy o Proportion of patients having had parathyroidectomy o Distribution of numbers of parathyroidectomies con	—

Measure

Time frame

As of 31/10/2017: % patients with all stipulated biochemical markers within 25%, 50%, 100% of target range, and more than 100% outside target range, according to: • UK Renal Association Clinical Guidelines • KDOQI Guidelines • KDIGO Clinical Practice Guideline % patients with all stipulated biochemical markers within target range at date of data collection and at 3 months prior to data collection according to: • UK Renal Association Clinical Guidelines, • KDOQI Guidelines, • KDIGO Clinical Practice Guideline Achievement of UK Renal Association Guideline targets (single, dual) Achievement of KDOQI Guideline targets (single, dual, triple) Achievement of KDIGO Guidelines targets (single, dual) Description of services and policies related to SHPT management: • Number of whole time equivalent consultant renal physicians per 100 dialysis patients • Number of whole time equivalent junior doctors per 100 dialysis patients • Number of whole time equivalent dietitians per 100 dialysis patients • Number of whole time equivalent bone disease specialist nurses per 100 dialysis patients • Number of whole time equivalent renal pharmacists per 100 dialysis patients • Number of whole time equivalent surgeons who conduct parathyroidectomies per 100 dialysis patients • Hospital guidelines used to shape clinical practice • Hospital policy regarding availability of cinacalcet • Hospital policy regarding availability of non-calcium containing phosphate binder • Hospital policy regarding parathyroidectomy o Proportion of patients having had parathyroidectomy o Distribution of numbers of parathyroidectomies con

—

Countries

England, United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026