Use of patient blood to treat air collecting around the lung

Early Autologous Blood-patch Pleurodesis versus Conservative Management for Treatment of Secondary spontaneous pneumothorax: a randomised controlled trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN75342605

Enrollment

Registered

2016-03-24

Start date

2012-11-01

Completion date

Unknown

Last updated

2016-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Secondary spontaneous pneumothorax Respiratory Secondary spontaneous pneumothorax

Interventions

Following chest drain insertion, participants are randomly allocated to one of two groups. Group 1: Participants have intra-pleural instillation of 50ml autologous blood into the chest drain on day 3

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Aged 18 years and over 2. Secondary spontaneous pneumothorax 3. Unfit or unwilling to have surgery

Exclusion criteria

Exclusion criteria: Not meeting the inclusion criteria.

Design outcomes

Primary

Measure	Time frame
Time between insertion of chest drain and air leak stoppage is measured through daily clinical observations.	—

Secondary

Measure	Time frame
Length of hospital stay is measured in days.	—

Countries

Egypt

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026