Effect of integrated interventions against schistosomiasis in rural Sudan

Effect of integrated interventions combining mass drug administration, community-led total sanitation, vector control, and primary health care strengthening against schistosomiasis on prevalence, incidence and reinfection among school-aged children and adults in rural areas of White Nile, North Kordofan, Gezira, Blue Nile, Khartoum, and Kassal states, Sudan

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN75328855

Enrollment

10000

Registered

2023-01-12

Start date

2023-01-22

Completion date

Unknown

Last updated

2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Prevention of schistosomiasis in school-aged children and adults in rural Sudan Infections and Infestations

Interventions

People in the intervention group will receive the interventions of community-led total sanitation, vector control, and primary health care strengthening from March 2023 through December 2023. During t

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: In each community, children aged 5–15 and other age group above 15 years are eligible.

Exclusion criteria

Exclusion criteria: People will be excluded from the study if they do not agree to be enrolled and/or examined. People with diarrhea will be also excluded.

Design outcomes

Primary

Measure	Time frame
Schistosomiasis infection status measured using the following methods: 1. Schistosomiasis mansoni by Kato Katz methods and the circulating cathodic antigen (CCA) in January 2023 (baseline survey), and at 6 months (August 2023) and 10 months (December 2023) after the baseline survey 2. Schistosomiasis haematobium by urine centrifugation and dipstick methods in January 2023, and at 6 months (August 2023) and 10 months (December 2023) after the baseline survey	—

Measure

Time frame

Schistosomiasis infection status measured using the following methods: 1. Schistosomiasis mansoni by Kato Katz methods and the circulating cathodic antigen (CCA) in January 2023 (baseline survey), and at 6 months (August 2023) and 10 months (December 2023) after the baseline survey 2. Schistosomiasis haematobium by urine centrifugation and dipstick methods in January 2023, and at 6 months (August 2023) and 10 months (December 2023) after the baseline survey

—

Secondary

Measure	Time frame
1. Latrine coverage meaured using a household-based survey questionnaire in January 2023 (baseline survey), and at 6 months (August 2023) and 10 months (December 2023) after the baseline survey 2. Snail density measured using scooping methods with a standardized scoop comprised of a flat wire mesh size (1.5 mm mesh size) mounted on a metal frame (40×30 cm) with a 2 m long metal handle on a quarterly basis from March through December 2023	—

Measure

Time frame

1. Latrine coverage meaured using a household-based survey questionnaire in January 2023 (baseline survey), and at 6 months (August 2023) and 10 months (December 2023) after the baseline survey 2. Snail density measured using scooping methods with a standardized scoop comprised of a flat wire mesh size (1.5 mm mesh size) mounted on a metal frame (40×30 cm) with a 2 m long metal handle on a quarterly basis from March through December 2023

—

Countries

Sudan

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Mar 14, 2026