Topic: Medicines for Children Research Network
Conditions
Interventions
Primary Intervention, Commencement of Glycopyrronium oral medication or Hyoscine patch.
Secondary intervention, Adjustments to dosing of Glycopyrronium or Hyoscine.
Tertiary Intervention, Appointment
Sponsors
Newcastle upon Tyne Hospitals NHS Foundation Trust (UK)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Treatment naive children, with nonprogressive neurodisability, who require Glycopyrronium or Hyoscine to reduce drooling 2. No contraindication to either medication 3. Age between 36 months and below 16 years; Target Gender: Male & Female
Exclusion criteria
Exclusion criteria: 1. Children who have received medical or surgical interventions for drooling 2. Children with medical conditions for which either medication is contraindicated 3. Children whose parents are considered unable to follow the study protocol 4. Parents without mobile or home telephone (required for communication with research registrar and assistant) 5. Parents whose use of English would not allow them to understand the issues in the 6. Consent form or be able to take part in the phone calls with the Trial Research Paediatrician and Trial Outcome Assessor
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Drooling Impact Scale score at 4 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| Not provided at time of registration | — |
Countries
United Kingdom
Outcome results
None listed