Low-fit and high-fit young (18-40 years) adults Other
Conditions
Interventions
Current interventions as of 05/04/2024:
This study will use a randomized, placebo-controlled, double-blinded, acute human study in healthy young adults, aged 18-40 yrs, to investigate the impact of fl
Sponsors
University of Birmingham
Eligibility
Sex/Gender
All
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1. Healthy male or female 2. Aged 18-40 years old 3. Have a VO2max of 41 ml/kg/min in Females or 50 ml/kg/min in Males
Exclusion criteria
Exclusion criteria: 1. Consumption of more than 21 units of alcohol per week 2. A history of cardiopulmonary, cerebrovascular, musculoskeletal affecting the limbs, respiratory, metabolic, metabolic, liver, inflammatory diseases, or neurological illness. This may include but is not limited to; blood-clotting disorders, hypertension (BP > 140/90 mmHg), diabetes mellitus, anaemia, asthma (only if you take regular/daily medication or require medication before or after exercise), immune conditions, elevated cholesterol, smokers, or have recently had prolonged bed rest. 3. Known allergy to berries 4. Consumption of a weight-reducing dietary regiment 5. Taking any dietary supplements, including fatty acids and vitamins 6. Long-term medication or have been on antibiotics for the last 3 months 7. Do not have an infection at present (e.g., cold) 8. Do not have a VO2max between Female: >34 and 40 and <50 ml/kg/min
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Prefrontal cortical levels of oxygenated haemoglobin concentrations measured using functional Near-Infrared Spectroscopy (fNIRS) during exercise before and 1 h following consumption of blueberry or placebo supplement | — |
Secondary
| Measure | Time frame |
|---|---|
| Previous secondary outcome measures: 1. Executive function accuracy and reaction time will be measured using the following three tasks during and post-exercise, prior to and 1.5 h following, consumption of blueberry or placebo supplement: 1.1. Modified Attention Network Task (post-exercise) measures response to cognitive load 1.2. Switch Task (post-exercise) considers cognitive flexibility with participants responding to stimuli according to two different paradigms (or rule) shifts 1.3. Modified Stroop Task (during exercise) assesses selective attention and prepotent response inhibition during decision making 2. Prefrontal cortical levels of oxygenated and deoxygenated haemoglobin concentrations during cognitive performance measured using functional Near-Infrared Spectroscopy (fNIRS) before and 1.5 h following consumption of blueberry or placebo supplement 3. Common carotid artery, internal carotid artery, and vertebral artery cerebral blood flow at rest measured using duplex ultrasound before and 2 h after blueberry or placebo supplement 4. Endothelial function - Flow-mediated dilatation of the brachial artery measured using duplex ultrasound using standardised procedures before and 2.5 h post blueberry or placebo supplement Previous secondary outcome measures: 1. Executive function accuracy and reaction time will be measured using the following three tasks during and post-exercise, prior to and 1.5 h following, consumption of blueberry or placebo supplement: 1.1. Modified Attention Network Task (post-exercise) measures response to cognitive load 1.2. Switch Task (post-exercise) considers cognitive flexibility with participants responding to stimuli according to two different paradigms (or rule) shifts 1.3. Modified Stroop Task (during exercise) assesses selective attention and prepotent response inhibition during decision making 2. Prefrontal cortical levels of oxygenated and deoxygenated haemoglobin concentrations during cognitive performance measured using fu | — |
Countries
England, United Kingdom
Contacts
Public ContactCatarina;Alexander Rendeiro;Friend
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Outcome results
None listed