Schizophrenia Mental and Behavioural Disorders Schizophrenia
Conditions
Interventions
Cognitive remediation therapy versus usual care
Sponsors
King's College London (UK)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. A diagnosis of schizophrenia according to the Diagnostic and Statistical Manual, 4th (DSM IV); had a first episode while still a teenager and their duration of illness was 3 years or less 2. Cognitive difficulties in cognitive flexibility (below the 16th centile on the Wisconsin Card Sort Test) and/or memory (poor performance on the Rivermead Behavioural Memory Test) 3. Difficulties in social functioning (at least one problem on the Social Behaviour Scale) 4. Stable medication, in terms of type and dose, for at least one month prior to inclusion
Exclusion criteria
Exclusion criteria: 1. Evidence of organic brain disorder (e.g. epilepsy) 2. A diagnosis of current substance abuse as defined by the DSM IV 3. A plan to change medication during the trial
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Cognitive flexibility (number of categories achieved on the Wisconsin Card Sort Test [WCST] Heaton et al.) 2. Memory (raw score from Digit Span: Wechsler Adult Intelligence Scale-III [WAIS-III] Wechsler,1981) 3. Planning (modified six elements) | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Social Behaviour Schedule ([SBS] Wykes and Sturt, 1986) for social functioning 2. Brief Psychiatric Rating Scale (for symptoms) using Lukoff et al. version and Shaffer Factor Scores 3. Quality of Life Scale (for social inclusion) 4. Rosenberg Self Esteem Scale (Rosenberg, 1965) | — |
Countries
United Kingdom
Outcome results
None listed