Polyphenols bioavailability study on wine

Bioavailability of polyphenols from wine and dealcoholized wine: a cross-over, randomized and double blind trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN74654313

Enrollment

Registered

2014-08-06

Start date

2014-03-15

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Concentration of phenolic metabolites in urine Not Applicable

Interventions

Intervention 1: 339 ml of water Intervention 2: 339 ml of wine Intervention 3: 417 ml of dealcoholized wine Before each intervention, participants will follow a 3-day washout period, avoiding consumi

Eligibility

Sex/Gender

Male

Inclusion criteria

Inclusion criteria: Healthy adult males, aged 20-40 years

Exclusion criteria

Exclusion criteria: 1. Previous history of cardiovascular disease (ischemic heart disease - angina or recent or old myocardial infarction, cerebral vascular accident, or peripheral vascular disease) 2. Homeostatic disorders 3. Any several chronic diseases 4. Hypertension or dyslipidemia 5. Grape intolerance or allergic 6. Smoking subjects 7. Alcoholism 8. Other toxic abuse

Design outcomes

Primary

Measure	Time frame
1. Polyphenols will be identified through liquid chromatography coupled to Orbitrap mass spectrometry 2. Concentrations of polyphenols will be determined by liquid chromatography coupled to tandem mass spectrometry (LC?MS/MS)	—

Countries

Spain

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026