Stroke Circulatory System Stroke
Conditions
Interventions
Patients of group A are being treated according to the current standards of therapy. With respect to antibiotics, they are fully and effectively treated as soon as an antibiotic medication is indicate
Sponsors
Charité - University Medicine Berlin (Charité - Universitätsmedizin Berlin) (Germany)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: The double blind, randomised and controlled study will be carried out on two groups of about 40 patients each. Since patients with large infarctions in the territory of the middle cerebral artery and a subsequent severe neurological deficit (National Institutes of Health-Stroke-Scale [NIHSS] greater than 11) have the highest risk of pneumonia, we include only this subpopulation of stroke patients in our study. Inclusion criteria: 1. Severe ischemic strokes in MCA territory (area greater than 50% in cerebral computed tomography [CCT], NIHSS greater than 11) 2. Within 36 hours after stroke onset 3. Older than 18 years 4. No infection 5. No intracerebral bleeding
Exclusion criteria
Exclusion criteria: 1. Immunosupressive therapy 2. Pregnancy 3. Antibacterial therapy within the last 24 hours before inclusion 4. Contraindication for moxifloxacin
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Not provided at time of registration | — |
Secondary
| Measure | Time frame |
|---|---|
| Not provided at time of registration | — |
Countries
Germany
Outcome results
None listed