Skip to content

The effect of hyaluronidase on dispersal of local anaesthetic solution after sub-Tenon's injection

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN74331160
Enrollment
19
Registered
2005-09-30
Start date
2004-03-24
Completion date
Unknown
Last updated
2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Surgery: Anaesthesia Surgery Anaesthesia

Interventions

1. Anaesthetic fluid with hyaluronidase 2. Anaesthetic fluid without hyaluronidase

Sponsors

Record Provided by the NHSTCT Register - 2005 Update - Department of Health (UK)
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Consecutive patients presenting for routine cataract extraction surgery will be approached to enrol in the study. They are mostly elderly patients (from previous studies in Leeds age range 65-80 years)

Exclusion criteria

Exclusion criteria: 1. Allergy to local anaesthetic 2. Inability/refusal to give informed consent 3. Any patient with pre existing extra ocular muscle palsy, patients with single eye who could be unable to follow a target so assessment of akinesia would be impossible.

Design outcomes

Primary

MeasureTime frame
Ultrasound measured depth of local anaesthetic solution behind the eye at 1, 3 and 5 minutes after the injection.

Secondary

MeasureTime frame
Akinesia, pain scores and surgical satisfaction.

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026