Effects of prolonged anti blood clot treatment after colorectal surgery

Minimal effect of universal extended prophylaxis on rates of venous thromboembolic events after colorectal surgery in a tertiary care center. Is compliance the problem?

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN74314169

Enrollment

270

Registered

2019-07-10

Start date

2017-11-01

Completion date

Unknown

Last updated

2021-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colon and rectal surgery, venous thromboembolism Surgery

Interventions

Universal extended (30 days after surgery) prophylaxis with enoxaperin. Enoxaparin dose was weight based and used for 30 days after surgery. Survey was done 30 days after surgery.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: All patients undergoing colon and rectal surgery at BIDMC between 11/1/2017 and 10/31/2018

Exclusion criteria

Exclusion criteria: 1. Patients with contraindication for use of low molecular weight heparin 2. Patients already on anticoagulation for other conditions

Design outcomes

Primary

Measure	Time frame
1. Complications from extended use of enoxaparin, measured using chart review and phone interview at 30 days after surgery 2. Compliance with extended prophylaxis regimen, measured using phone survey at 30 days after surgery	—

Secondary

Measure	Time frame
1. Rates of VTE measured using chart review and NSQIP data collection at 30 days after surgery 2. Other complications measured using chart review at 30 days after surgery	—

Countries

United States of America

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026