Chronic fatigue syndrome (CFS) Mental and Behavioural Disorders Chronic fatigue syndrome
Conditions
Interventions
1. Pragmatic rehabilitation
2. Supportive listening
3. Treatment as usual by GP
Sponsors
University of Manchester (UK)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients 18 and over, who fulfil the Oxford criteria for CFS (Sharpe et al. 1991) [Prior to Feb'2005 the criteria was the Fukuda criteria], and who have a principal complaint of fatigue. Patients must score 4 or more on the 11-item Chalder fatigue scale, and 70% or less on the SF-36 physical functioning scale.
Exclusion criteria
Exclusion criteria: 1. Patients whose fatigue is explained by any active medial condition 2. Patients with schizophrenia, bipolar disorder, dementia, eating disorder, substance abuse, morbid obesity 3. Patients with current suicidal ideation 4. Patients with anti-social, borderline or paranoid personality disorder 5. Patients who cannot read or write English sufficiently well to participate 6. Patients who are incapable of giving informed consent
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| 1. A timed step-test to provide an objective measure of the patient?s exercise tolerance and cardiovascular fitness 2. Scores on the HAD to provide measures of depression and anxiety 3. A brief four-item sleep scale | — |
Primary
| Measure | Time frame |
|---|---|
| The primary outcome measures will be patient-rated to avoid observer bias, and will be supplemented with an objective measure of the patient?s exercise tolerance. These will be: 1. Score on the physical functioning scale of the SF-36 2. Cost-effectiveness using the Euroquol 3. The score on the 11-item Fatigue Scale | — |
Countries
United Kingdom
Outcome results
None listed