Strategies to reduce the social gradient in bowel cancer screening: the ASCEND project

Conditions

Colorectal cancer Cancer Malignant neoplasm of rectosigmoid junction

Smith SG, Wardle J, Atkin W, Raine R, McGregor LM, Vart G, Morris S, Duffy SW, Moss S, Hackshaw A, Halloran S, Kralj-Hans I, Howe R, Snowball J, Handley G, Logan RF, Rainbow S, Smith S, Thomas M, Counsell N, von Wagner C.

2017-08-147 citations

10.1186/s12885-017-3512-1

Testing innovative strategies to reduce the social gradient in the uptake of bowel cancer screening: a programme of four qualitatively enhanced randomised controlled trials

Rosalind Raine, Wendy Atkin, Christian von Wagner, Stephen W. Duffy, Ines Kralj‐Hans et al. (26 authors)

Programme Grants for Applied Research2017-03-014 citations

10.3310/pgfar05080

Reducing the Social Gradient in Uptake of the NHS Colorectal Cancer Screening Programme Using a Narrative-Based Information Leaflet: A Cluster-Randomised Trial

Lesley McGregor, Christian von Wagner, Wendy Atkin, Ines Kralj‐Hans, Stephen P Halloran et al. (20 authors)

Gastroenterology Research and Practice2016-01-0113 citations

10.1155/2016/3670150

Effects of evidence-based strategies to reduce the socioeconomic gradient of uptake in the English NHS Bowel Cancer Screening Programme (ASCEND): four cluster-randomised controlled trials.

Wardle J, von Wagner C, Kralj-Hans I, Halloran SP, Smith SG, McGregor LM, Vart G, Howe R, Snowball J, Handley G, Logan RF, Rainbow S, Smith S, Thomas MC, Counsell N, Morris S, Duffy SW, Hackshaw A, Moss S, Atkin W, Raine R.

2015-12-09103 citations

10.1016/s0140-6736(15)01154-x

Interventions

All of the interventions listed below will be tested against usual practice in Bowel Cancer Screening Programme. 1. Gist intervention: This is an information leaflet which offers two levels of infor

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Men and women eligible to be screened for bowel cancer in England 2. Aged between 60-74 years

Exclusion criteria

Exclusion criteria: In Intervention 3 (GP endorsed invitation letters) we will only be able to randomise eligible people to receive this intervention if they are registered with practices that have agreed to endorse the BCSP. We estimate that only about 30% of all GP practices in England will consent to their name being used on BCSP invitation letters so the majority of eligible people will receive the usual invitation letters.

Design outcomes

Primary

Measure	Time frame
The proportion of people in each socioeconomic group returning an adequate faecal occult blood test (FOBt) within 18 weeks of being sent an invitation. Socioeconomic groups will be identified using Index of Multiple Deprivation (IMD) quintile scores	—

Secondary

Measure	Time frame
1. Time taken to return FOBt by IMD quintile 2. Proportion of spoilt kits and their relationship to IMD quintile 3. Proportion of non-delivered kits by IMD quintile 4. Incremental cost per screening invitation 5. Incremental cost per screening invitation, both by IMD quintile and overall 6. All of the above outcomes analysed using other socioeconomic variables	—

Countries

United Kingdom

Outcome results

None listed