Comparing oil based ointment versus standard practice for the treatment of moderate burns in Greece: A cost effectiveness evaluation

Moist exposed burn ointment versus povidone iodine plus bepanthenol for patients with moderate burns (TBSA<15%)

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN74058791

Enrollment

214

Registered

2010-11-12

Start date

2002-01-05

Completion date

Unknown

Last updated

2021-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Burns Injury, Occupational Diseases, Poisoning Burn and corrosion, body region unspecified

Interventions

Patients will be randomised to receive either: 1. Moist exposed burn ointment (MEBO), applied twice per day with the assistance of nursing staff 2. Povidone iodine plus

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Total Burns Surface Area (TBSA) <15%. 2. Thermal burns 3. No need of surgical operation 4. Either sex, aged 18-75

Exclusion criteria

Exclusion criteria: Systematic diseases (cancer and diabetes)

Design outcomes

Primary

Measure	Time frame
1. Mean reduction in days of in-hospital stay for patients in both groups (standard length of stay according to the experts=10 days) 2. Time of recovery for patients with superficial partial thickness burns (Transepidermal Water Loss [TEWL] <60 gr/m2/h) using the TEWL indicator, recovery defined as 50% reduction of the TEWL on the first day	—

Secondary

Measure	Time frame
1. Pain A visual analogue scale of 1 to 10 is used for pain measurement (0 = no pain; 1-2 = slight pain; 3-4 = mild pain; 5 = moderate pain; 6-9 = moderately severe pain; 10 = severe pain). Pain scores were recorded twice daily by the doctors. Pain medication is given upon patient demand 2. Clinical evaluation of the appearance of burn limits A clinical evaluation of the appearance of burn limits is made each day by the doctor. We have used a binary and a continuous variable to quantify these criteria. The modalities of the first variable are: 2.1. Healthy appearance of burn limits 2.2. No Healthy appearance (presenting redness, swelling, other)	—

Measure

Time frame

1. Pain A visual analogue scale of 1 to 10 is used for pain measurement (0 = no pain; 1-2 = slight pain; 3-4 = mild pain; 5 = moderate pain; 6-9 = moderately severe pain; 10 = severe pain). Pain scores were recorded twice daily by the doctors. Pain medication is given upon patient demand 2. Clinical evaluation of the appearance of burn limits A clinical evaluation of the appearance of burn limits is made each day by the doctor. We have used a binary and a continuous variable to quantify these criteria. The modalities of the first variable are: 2.1. Healthy appearance of burn limits 2.2. No Healthy appearance (presenting redness, swelling, other)

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Countries

Greece

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Mar 27, 2026