Does the treatment of maternal Attention Deficit Hyperactivity Disorder enhance the effectiveness of parent management training for children's attention deficit hyperactivity disorder?

Conditions

Attention Deficit Hyperactivity Disorder (ADHD) in children and their mothers Mental and Behavioural Disorders Hyperkinetic disorders

Geissler JM, Vloet TD, Strom N, Jaite C, Graf E, Kappel V, Warnke A, Jacob C, Hennighausen K, Haack-Dees B, Schneider-Momm K, Matthies S, Rösler M, Retz W, Hänig S, von Gontard A, Sobanski E, Alm B, Hohmann S, Poustka L, Colla M, Gentschow L, Freitag CM, Häge A, Holtmann M, Becker K, Philipsen A, Jans T.

2019-12-052 citations

10.1007/s00787-019-01451-0

Sequential treatment of ADHD in mother and child (AIMAC study): importance of the treatment phases for intervention success in a randomized trial.

Hautmann C, Döpfner M, Katzmann J, Schürmann S, Wolff Metternich-Kaizman T, Jaite C, Kappel V, Geissler J, Warnke A, Jacob C, Hennighausen K, Haack-Dees B, Schneider-Momm K, Philipsen A, Matthies S, Rösler M, Retz W, von Gontard A, Sobanski E, Alm B, Hohmann S, Häge A, Poustka L, Colla M, Gentschow L, Freitag CM, Becker K, Jans T.

2018-12-13

10.1186/s12888-018-1963-9

A multicentre randomized controlled trial on trans-generational attention deficit/hyperactivity disorder (ADHD) in mothers and children (AIMAC): an exploratory analysis of predictors and moderators of treatment outcome

Charlotte Jaite, Betteke Maria van Noort, Timo D. Vloet, Erika Graf, Viola Kappel et al. (28 authors)

Zeitschrift für Kinder- und Jugendpsychiatrie und Psychotherapie2018-08-074 citations

10.1024/1422-4917/a000602

ESCAlate - Adaptive treatment approach for adolescents and adults with ADHD: study protocol for a randomized controlled trial.

Zinnow T, Banaschewski T, Fallgatter AJ, Jenkner C, Philipp-Wiegmann F, Philipsen A, Retz W, Sobanski E, Thome J, Rösler M.

2018-05-187 citations

10.1186/s13063-018-2665-9

Does the efficacy of parent–child training depend on maternal symptom improvement? Results from a randomized controlled trial on children and mothers both affected by attention-deficit/hyperactivity disorder (ADHD)

Alexander Häge, Barbara Alm, Tobias Banaschewski, Katja Becker, Michael Colla et al. (27 authors)

European Child & Adolescent Psychiatry2018-01-237 citations

10.1007/s00787-018-1109-0

Does intensive multimodal treatment for maternal <scp>ADHD</scp> improve the efficacy of parent training for children with <scp>ADHD</scp> ? A randomized controlled multicenter trial

Thomas Jans, Christian Jacob, Andreas Warnke, Ulrike Zwanzger, Silke Groß‐Lesch et al. (27 authors)

Journal of Child Psychology and Psychiatry2015-06-3051 citations

10.1111/jcpp.12443

A randomized controlled multicentre trial on the treatment for ADHD in mothers and children: enrolment and basic characteristics of the study sample.

Jans T, Graf E, Jacob C, Zwanzger U, Gross-Lesch S, Matthies S, Perlov E, Hennighausen K, Jung M, Rösler M, Schulte-Altedorneburg M, von Gontard A, Hänig S, Sobanski E, Alm B, Poustka L, Bliznak L, Colla M, Gentschow L, Burghardt R, Salbach-Andrae H, Becker K, Holtmann M, Freitag C, Warnke A, Philipsen A.

2012-10-1610 citations

10.1007/s12402-012-0092-4

Does the treatment of maternal attention deficit and hyperactivity disorder (ADHD) enhance the efficacy of a behavioural parent training for the treatment of their children's ADHD? Study protocol of a randomized controlled multicentre trail.

Jans T, Philipsen A, Graf E, Ihorst G, Gerlach M, Warnke A.

2009-04-2412 citations

10.1007/s12402-009-0004-4

Interventions

Two-armed design: Experimental Group (EG): treatment of mother's ADHD with methylphenidate and a specific group psychotherapy program (12 weekly sessions, followed by monthly sessions,

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: All patients: 1. Voluntary and written informed consent of the mother, the child and other persons having the care and custody of the child Children: 1. Aged six to 12 years 2. Diagnosis of ADHD according to Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV) criteria 3. No medication or on stable medication for at least four weeks before baseline assessment Mothers: 1. Diagnosis of ADHD according to DSM-IV criteria 2. A score of 30 or more on the short version of the Wender-Utah-Rating-Scale 3. Aged 18 to 60 years, inclusive 4. Chronic course of ADHD symptoms from childhood to adulthood, onset of ADHD symptoms before the age of seven 5. No abnormality detected on physical examination, routine blood testing (blood count, renal, hepatic and thyroid function), Electrocardiogram (ECG) and Electroencephalogram (EEG)

Exclusion criteria

Exclusion criteria: All patients: 1. Participation in another clinical trial 2. Specific interventions for the treatment of ADHD within the last six months before screening 3. Need for inpatient treatment Children: 1. Intelligence Quotient (IQ) less than 80 2. Pervasive developmental disorder, psychosis, schizophrenia, bipolar disorder, severe depressive episode Mothers: 1. IQ less than 80 2. Schizophrenia, bipolar disorder, borderline personality disorder, antisocial personality disorder, suicidal or self-injurious behaviour, autism, motor tics, Tourette's syndrome 3. Substance abuse/dependence within six months prior to screening. Episodic abuse is not an exclusion criterion 4. Neurological diseases, seizures, glaucoma, uncontrolled hypertension 5. Current eating disorder/low weight (Body Mass Index [BMI] less than 20) 6. Pregnancy or breast-feeding

Design outcomes

Primary

Measure	Time frame
Primary endpoint is the extent of externalising symptoms in the children: 1. ADHD-ODD-Scale (ODD: Oppositional Defiant Disorder): number of symptoms of ADHD and ODD present during the last two weeks before assessment (ADHD-section and ODD-section of the Kiddie Schedule for Affective Disorders and Schizophrenia [KIDDIE-SADS], blind investigator-rating)	—

Secondary

Measure	Time frame
Children: 1. ADHD-section and ODD-section of the KIDDIE-SADS (diagnosis +/-, responders-nonresponders: 30 percent reduction of the ADHD-ODD-Scale, blind investigator-rating) 2. Externalising and internalising symptoms: Strength and Difficulties Questionnaire (SDQ) (mother and teacher report) 3. Family functioning: Home-Situations-Questionnaire (HSQ, mother-report) 4. Impact of the child's symptoms on the family: Family Impact Questionnaire (FIQ, mother-report) 5. Process-quality, related to parent training (Fragebogen zur Beurteilung der Behandlung, FBB, mother- and therapist-report) Mothers: 1. Symptom-Checklist (SCL-90-R, self-rating mother) 2. Conners Adult ADHD Rating Scale (CAARS-S:L, self-rating mother; CAARS-O:L, blind investigator rating)	—

Measure

Time frame

Children: 1. ADHD-section and ODD-section of the KIDDIE-SADS (diagnosis +/-, responders-nonresponders: 30 percent reduction of the ADHD-ODD-Scale, blind investigator-rating) 2. Externalising and internalising symptoms: Strength and Difficulties Questionnaire (SDQ) (mother and teacher report) 3. Family functioning: Home-Situations-Questionnaire (HSQ, mother-report) 4. Impact of the child's symptoms on the family: Family Impact Questionnaire (FIQ, mother-report) 5. Process-quality, related to parent training (Fragebogen zur Beurteilung der Behandlung, FBB, mother- and therapist-report) Mothers: 1. Symptom-Checklist (SCL-90-R, self-rating mother) 2. Conners Adult ADHD Rating Scale (CAARS-S:L, self-rating mother; CAARS-O:L, blind investigator rating)

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Countries

Germany

Outcome results

None listed