A two-arm interventional study to evaluate the impact of Home and community management of Malaria with Artemisinin Combination Therapy (ACT) on under five childhood mortality in two rural health districts, Burkina Faso

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN73662821

Enrollment

5000

Registered

2005-11-25

Start date

2005-11-01

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Uncomplicated malaria Infections and Infestations Malaria

Interventions

1. Training of community-based drug distributors - Y1 2. Develop and implement a communication for behaviour change strategy - Y1 to Y3 3. Avail pre-packaged unit dosed ACTs (Coartem)

ACTs will be deployed at health facility (HF) and community level in the intervention areas, at HF level only in control areas - Y2 and Y3 4. Implement a community based vital statistics monitoring sy

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Children aged 6 to 59 months with fever (uncomplicated malaria) 2. Signs of severe disease

Exclusion criteria

Exclusion criteria: 1. Known hypersensitivity to the drug 2. Refusal to give informed consent

Design outcomes

Primary

Measure	Time frame
Overall and malaria-specific mortality	—

Secondary

Measure	Time frame
1. Incidence of severe malaria 2. Prevalence of severe anaemia	—

Countries

Burkina Faso

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026