Infant and child health status Not Applicable
Conditions
Interventions
Randomised double-blind placebo-controlled trial of 25 g/d LNS (containing macronutrients and 23 micronutrients) under Good Clinical Practice (GCP) standards. Supplement will be administered by the ca
Sponsors
Medical Research Council (MRC) (UK)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Children aged 6 months - 5 years (either sex) from the West Kiang Region of The Gambia self-presenting to the clinic at MRC Keneba, West Kiang, The Gambia
Exclusion criteria
Exclusion criteria: 1. Children from regions other than the West Kiang Region of The Gambia 2. Children known to be asthmatic or allergic to peanuts 3. Children known to be involved in another trial 4. Children with known haemoglobinopathies 5. Children with severe malnutrition (weight-for-height SD-score less than -3 or/and presence of oedema) (World Health Organization [WHO] 2000) 6. Children presenting to the clinic but called rather than self-referred (e.g. for DSS purposes and immunisations)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Health status as indicated by the frequency of self-referred clinic return attendances within 12 months from baseline specifying clinical diagnoses at each presentation to profile disease patterns and growth (weight, height/length, mid-upper arm circumference (MUAC)) at four points over 6 months. | — |
Secondary
| Measure | Time frame |
|---|---|
| Micronutrient status and standard haematology in a random subgroup of 300 subjects, measured at day 10 and at 12 weeks from start of supplementation. | — |
Countries
Gambia
Outcome results
None listed