The arcOGEN study: a genome wide association study of osteoarthritis

A non-randomised observational trial in participants with primary osteoarthritis who will be used for mapping osteoarthritis susceptibility genes by genome-wide association scan

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ISRCTN

Registry ID

ISRCTN73561469

Enrollment

8000

Registered

2010-05-27

Start date

2008-03-01

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Topic: Musculoskeletal

Interventions

There is no intervention in this trial. Recruited participants have a blood sample taken for a DNA test and a questionnaire will be answered. No treatments are given.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Primary osteoarthritis ascertained by joint replacement of the hip or the knee 2. Male and female, lower age limit of 40 years

Exclusion criteria

Exclusion criteria: Secondary forms of osteoarthritis or non-osteoarthritic diseases that result in joint replacement surgery

Design outcomes

Primary

Measure	Time frame
Questionnaire, completed at time of blood sampling	—

Secondary

Measure	Time frame
No secondary outcome measures	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026