Safety and efficacy of cardiac output invasive monitoring in elderly patients

Safety and efficacy of pulse-induced contour cardiac output monitoring in elderly patients with coronary artery disease and severe heart failure at coronary care units

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ISRCTN

Registry ID

ISRCTN73335561

Enrollment

191

Registered

2021-07-09

Start date

2016-01-01

Completion date

Unknown

Last updated

2022-11-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Elderly patients with severe heart failure Circulatory System Heart failure

Interventions

Between January 2016 and July 2020, 190 elderly patients with severe heart failure were enrolled and assigned randomly (using a random number generator) to the PiCCO group (89 patients) or noninvasive

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Known history of coronary heart disease 2. Orthopnea (inability to lie down) 3. Wet rales in the lungs 4. Edema in the lower extremities 5. Echocardiography showing left ventricular end-diastolic diameter of >50 mm and left ventricular ejection fraction(LVEF) of <50%, or chest X-ray showing pulmonary congestion or edema 6. Type I respiratory failure (partial pressure of oxygen of <50 mm Hg even after oxygen therapy, requiring tracheal intubation and mechanical ventilation after conventional treatments, such as cardiotonic therapy, diuretics, and vasoactive drugs). 7. Aged 65 - 100 years

Exclusion criteria

Exclusion criteria: 1. Heart failure 2. Uncontrolled severe infection, and pulmonary diseases

Design outcomes

Primary

Measure	Time frame
Length of hospital stay measured using patient records at the end of the study	—

Secondary

Measure	Time frame
There are no secondary outcome measures	—

Countries

China

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026