Beer consumption Nutritional, Metabolic, Endocrine
Conditions
Interventions
Male volunteers:
Intervention 1: Administration of 330 mL beer (14.5 g ethanol)
Intervention 2: Administration of 660 mL beer (29 g ethanol)
Intervention 3: Administration of 990 mL beer (43.5 g et
Sponsors
Center for Biomedical Research in Pathophysiology of Obesity & Nutrition (Ciber Fisiopatología de la Obesidad Nutrición)(Spain)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Young healthy volunteers of age 28±3 years, body mass index 22.69±2.69 kg/m2
Exclusion criteria
Exclusion criteria: 1. Previous history of cardiovascular disease (ischemic heart disease criteria - angina, recent or old myocardial infarction, cerebral vascular accident or peripheral vascular disease) 2. Homeostatic disorders 3. Any several chronic diseases 4. Hypertension or dyslipidemia 5. Smoking subjects 6. Alcoholism 7. Other toxic abuse
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Concentrations of urinary prenylflavanoids will be determined by liquid chromatography coupled to tandem mass spectrometry (LC?MS/MS). These determinations will be carried out in first morning urine samples collected the day before the first intervention and in the subsequent mornings following each intervention. Creatinine adjustment will be used to normalize analyte concentrations in these urine samples. | — |
Secondary
| Measure | Time frame |
|---|---|
| No secondary outcome measures | — |
Countries
Spain
Outcome results
None listed