Misoprostol administered sublingually for second trimester pregnancy termination

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN72965671

Enrollment

680

Registered

2004-04-01

Start date

2001-12-01

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Induced abortion Pregnancy and Childbirth Abortion

Interventions

Misoprostol (0.4 mg) either vaginally or sublingually every three hours up to five doses. Approximate duration of involvement in the study for each subject: first follow up at 15 days post-treatment,

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: 1. Healthy women 2. Eligible for and requesting legal termination of second trimester pregnancy

Exclusion criteria

Exclusion criteria: No exclusion criteria

Design outcomes

Primary

Measure	Time frame
1. The effectiveness to induce complete or partial abortion/induction-to-abortion interval 2. The frequency of side effects 3. Acceptability of treatment to women	—

Secondary

Measure	Time frame
No secondary outcome measures	—

Countries

Armenia, Georgia, Hungary, India, Slovenia, South Africa, Viet Nam, Zambia

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Apr 4, 2026