Body swelling after surgery: the influence of poor fluid intake, inflammation and the choice of infusion fluid

Mechanisms of oedema after general surgery; a randomized clinical trial of the choice of fluid and the influences of preoperative dehydration, inflammation and surgical stress

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN72860921

Enrollment

Registered

2014-06-12

Start date

2012-06-01

Completion date

Unknown

Last updated

2018-02-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

General surgery Surgery

Interventions

Randomization between using a colloid or a crystalloid fluid for plasma volume support during the surgery. Blood and urine sampling. Recording of postoperative complications according to a prospective

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Adult patients (age >18 years) scheduled for surgery in general anaesthesia lasting for > 30 minutes

Exclusion criteria

Exclusion criteria: 1. Endocrinological disease (such as diabetes) 2. Kidney disease 3. Dementia 4. Heart disease that affects physical performance 5. Difficulty understanding the Swedish language

Design outcomes

Primary

Measure	Time frame
Increase in body weight from before up to the morning after surgery	—

Secondary

Measure	Time frame
1. Dehydration as evaluated by urine samples before surgery 2. Stress and inflammation as detected by serum cortisol and CRP in the morning after the surgery was performed	—

Countries

Sweden

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026