Persistent vegetative or minimally conscious state Signs and Symptoms Persistent vegetative or minimally conscious state
Conditions
Interventions
Tilt table therapy with or without an integrated stepping device for three weeks
Sponsors
Neurologische Klinik Bad Aibling (Germany)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. In a persistent vegetative or minimally conscious state after traumatic brain injury, intracerebral hemorrhage or ischemic stroke, or in a minimally conscious state after hypoxia 2. Aged 18 to 70 years 3. Time since injury not more than six months 4. Not yet mobilised into standing for more than 30 minutes 5. Informed consent of legal proxy
Exclusion criteria
Exclusion criteria: 1. Acute severe heart or lung disease (e.g. pneumonia, heart attack during the last four weeks) 2. Cardiac pace maker 3. Severe osteoporosis 4. Contractures or severe spasticity of lower extremities 5. Pregnancy 6. Unstable fractures or decubiti on lower extremities
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Level of consciousness measured by the Coma Recovery Scale - revised after three weeks of treatment and three weeks follow-up | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Improvement in heart rate variability 2. To assess muscle tone/spasticity (modified Tardieu scale/Asworth scale) 3. To monitor reaction of blood pressure, heart rate and oxygen saturation during treatments 4. To assess Glasgow Outcome Score at discharge from hospital | — |
Countries
Germany
Outcome results
None listed