Anorexia nervosa Mental and Behavioural Disorders Anorexia nervosa
Conditions
Interventions
Participants will be randomised into one of the three arms:
1. Focal psychodynamic psychotherapy: 40 outpatient individual therapy sessions over 10 months according to a manual
2. Cognitive-behaviou
Sponsors
German Federal Ministry of Education and Research (BMBF) (Germany)
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1. Anorexia nervosa (AN) and subsyndromal AN (lacking 1 diagnostic criterion according to Diagnostic and Statistical Manual of Mental Disorders [DSM] IV such as amenorrhoea or body image disturbance) 2. Female 3. Aged 18 years or older 4. Body mass index (BMI) between 15.0 and 18.5 kg/m^2 5. Signed consent form
Exclusion criteria
Exclusion criteria: 1. Current substance abuse 2. Current neuroleptic medication 3. Current suicidal ideation 4. Psychotic disorder 5. Bipolar disorder 6. Serious unstable medical problems 7. Primary somatic illness 8. Pregnancy or lactation 9. Ongoing psychotherapy 10. Participation in other trials
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Current information as of 04/02/2009: Body mass index (BMI) at the end of the treatment (10 months after randomisation; T2). In the statistical analysis, the BMI at T2 willl be adjusted for the baseline BMI at T0. Initial information at time of registration: Individual changes in BMI between beginning and end of treatment, assessed at 4 and 10 months and at 13-month follow-up. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Morgan-Russell criteria 2. General psychopathology 3. Eating disorders psychopathology 4. Depression (Structured Clinical Interview for DSM-IV [SCID-I], Structured Inventory for Anorexic and Bulimic Syndromes [SIAB-EX], PHQ-D [The "Patient Health Questionnaire"]) 5. Quality of life (the 36-item Short Form health survey [SF-36]) Added as of 04/02/2009: 6. Process measure: therapeutic alliance (Helping Alliance Questionnaire [HAQ]) | — |
Countries
Germany
Outcome results
None listed