Fragility fractures and falls in community-dwelling older adults Injury, Occupational Diseases, Poisoning
Conditions
Interventions
Community-dwelling older adults aged 65 years and older who underwent an abdominal CT scan that included the hip were eligible to participate in the study. Enrolled participants were invited for a sin
Sponsors
Geneva University Hospitals and Faculty of Medicine
University of Bern
Eligibility
Sex/Gender
All
Age
65 Years to 105 Years
Inclusion criteria
Inclusion criteria: 1. Individuals aged 65 years and older 2. Community-dwelling older adult 3. Having obtained an abdominal CT including the hip (lesser trochanter of the femur visible)
Exclusion criteria
Exclusion criteria: 1. Aged <65 years or having a life expectancy of <1 year 2. Nursing home resident 3. Prior hip fracture or hip prosthesis, unilateral or bilateral 4. Suffering from a bone pathology such as bone metastatic cancer, multiple myeloma, Paget's disease, osteogenesis imperfecta 5. Permanently bedridden or in a wheel-chair 6. Have cognitive impairment with incapacity to provide informed consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Incident falls, prospectively recorded via phone calls during 3 years of follow-up 2. Incident fragility fractures, prospectively recorded via phone calls during 3 years of follow-up | — |
Secondary
| Measure | Time frame |
|---|---|
| Measured using patient records (unless otherwise noted) at baseline: 1. Bone imaging modalities: 1.1 Bone mineral density using DXA (lumbar spine, hip) 1.2 Bone microstructure and strength using high-resolution peripheral computerised quantitative tomography (HR-pQCT) images at distal radius and tibia (substudy) 2. Medical history: 2.1 Comorbidities 2.2 Medication 2.3 Falls during the 6 months prior to baseline examination 2.4 History of fractures (all-life) 3. Fall risk factors: 3.1 Physical performance tests (Short physical performance battery (SPPB), hand grip strength, timed up and go) 3.2 Vision acuity with SZB Bailey-Lovie chart 3.3 Physical activity measured with wrist-worn accelerometer (Axivity) and questionnaire 3.4 Cognitive status measured with Mini Mental State Examination (MMSE) 3.5 Fear of falling measured with Falls Efficacy Scale international (FES-I) and questionnaire 4. Soft tissue stiffness measurement over the gerater trochanter performed with the Myoton indentation device | — |
Countries
Switzerland
Contacts
Public ContactChristina Wapp
Outcome results
None listed