Hypercholesterolemia Nutritional, Metabolic, Endocrine Hypercholesterolemia
Conditions
Interventions
Test group: soy foods, viscous fiber foods (oats and barley etc.), almonds and other nuts, plant sterol margarine prescribed as routine advice or intensive advice
Control group: low sa
Sponsors
University of Toronto (Canada)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. 330 persons with hiperlipidemia of both sex, age groups 18 and older 2. Men and post menopausal women with Low-Density Lipoprotein (LDL)-cholesterol levels within 30% of their target goals who are prepared to make a serious commitment to dietary change
Exclusion criteria
Exclusion criteria: 1. Body mass index (BMI) >32 kg/m^2 2. Recent weight loss or gain 3. Recent stroke 4. Myocardial Infarction (MI) 5. Familial hypercholesterolemia, secondary causes of hypercholesterolemia (e.g. hypothyroidism unless treated, renal or liver disease) 6. Cholesterol lowering medications 7. Triglyceride (TG) less than 4.5, blood pressure (BP) more than 145/90 8. Diabetes or major disability or disease, including liver disease, renal failure or cancer
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| LDL-cholesterol | — |
Secondary
| Measure | Time frame |
|---|---|
| Total: High-Density Lipoprotein (HDL) cholesterol, TG, HDL-C, C-Reactive Protein (CRP), Homocysteine, glucose, insulin, waist circumference, blood pressure (BP), diet composition, body weight, and red cell fragility and plant sterol concentrations | — |
Countries
Canada
Outcome results
None listed