Myocardial metabolic flexibility and myocardial function in patients with complicated type 2 diabetes

Myocardial metabolic flexibility and myocardial function in patients with complicated type 2 diabetes: a prospective intervention study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN72259923

Enrollment

Registered

2011-03-30

Start date

2009-02-10

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type 2 diabetes mellitus Nutritional, Metabolic, Endocrine Non-insulin-dependent diabetes mellitus

Interventions

Two magnetic resonance imaging (MRI)-scans will be performed in all patients. One baseline MRI-scan will be performed while patients have used their regular diet. A second MRI-scan after a 3-day very

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with complicated type 2 diabetes mellitus, both men and women, age >18 years

Exclusion criteria

Exclusion criteria: 1. Myocardial infarction 2. Congenital cardiac disease 3. Kidney failure 4. Pregnancy or lactation 5. Contra-indications for magnetic resonance imaging (MRI)

Design outcomes

Primary

Measure	Time frame
1. Myocardial triglcyeride content measured using proton MR spectroscopy 2. Cardiac function-measured by MRI Measured at baseline and at day 4	—

Secondary

Measure	Time frame
1. Plasma free fatty acids-blood tests 2. Plasma glucose-blood tests 3. Waist fat Measured at baseline and at day 4	—

Countries

Netherlands

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026