Digestive System: Ulcerative colitis Digestive System Ulcerative colitis
Conditions
Interventions
Categorical data will be compared with chi-squared test, t-testing on Mann-Whitney U test will be used for continuous data depending on normality.
Sponsors
Record Provided by the NHSTCT Register - 2006 Update - Department of Health
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients with longstanding extensive colitis, with evidence of microscopic inflammation at a previous colonoscopy 2. Patients over 18
Exclusion criteria
Exclusion criteria: Pre-intubation: 1. Pregnant patients 2. Severe active colitis 3. Those unwilling or unable to give consent Pre-randomisation: 1. Those with poor bowel preparations 2. Unable to reach caecum due to stricture
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The study is to determine if the use of a narrow band of light can help detect more pre-cancerous or cancerous areas than the normal white light used for detection. The outcome measure is to determine the numbers of patients with at least one cancer in either group. | — |
Secondary
| Measure | Time frame |
|---|---|
| Added 17 July 2008: 1. Are more precancerous lesions found in total with NBI? 2. Are more advanced precancerous lesions found with NBI? 3. Are more patients found with more than one precancerous lesion with NBI? 4. How many lesions are successfully completely removed with endoscope? | — |
Countries
United Kingdom
Outcome results
None listed