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Can the levels of a cell signalling factor in menstrual blood be used as a test for endometriosis?

Diagnostic test of transforming growth factor-beta 1 (TGF-ß1) in menstrual blood with endometriosis

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN72218532
Enrollment
58
Registered
2023-06-30
Start date
2019-08-16
Completion date
Unknown
Last updated
2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Endometriosis Pregnancy and Childbirth

Interventions

Married women with suspected endometriosis aged from 25–35 years old (>35 years until before menopause), who agree to undergo operative laparoscopy, participate in the study and signed an informed con

Sponsors

Mohammad Hoesin Central General Hospital
Lead Sponsor
Sriwijaya University
Collaborator

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: Patients with suspected endometriosis who underwent laparoscopy ranging from 25–35 years of age and >35 years until before menopause, married, agreed to undergo operative laparoscopy, agreed to participate in the study and signed an informed consent

Exclusion criteria

Exclusion criteria: Patients with suspected malignancy, chronic inflammation, diabetic retinopathy, pregnancy, and use of GnRH agonists before laparoscopy

Design outcomes

Primary

MeasureTime frame
Mean TGF ß1 level in menstrual blood measured using enzyme-linked immunosorbent assay (ELIZA) during the first three days of menstruation

Secondary

MeasureTime frame
Diagnostic accuracy of TGF ß1 measured using the laparoscopy outcome of endometriosis recorded in patient medical notes at one timepoint

Countries

Indonesia

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 7, 2026