Alzheimer's Disease Nervous System Diseases Alzheimer's disease
Conditions
Interventions
The intervention group received a regular exercise programme.
The control group received normal medical care but no regular exercise programme.
Sponsors
Caisse Nationale d'Assurance Maladie des Travailleurs Salaries (CNAMT) (France)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. To have met the National Institute of Neurological and Communicative Diseases and Stroke/Alzheimer Disease and Related Disorders Association criteria for probable or possible AD 2. To have lived in the nursing-home for at least 2 months 3. To be able to transfer from a chair and walk for at least 6 meters without human assistance 4. To have a Mini-Mental State Examination (MMSE) score <25 Enrolment lasted two weeks.
Exclusion criteria
Exclusion criteria: 1. Evidence of vascular dementia or Parkinson disease 2. Planned transfer from the nursing home or surgery in the year to come 3. A cardiac condition that might deteriorate during exercise, such as unstable angina or severe congestive heart disease 4. Diagnosis of a terminal illness with a life expectancy less than 6 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary efficacy outcome was decline from baseline in Katz Index ADL score compared with the control group at 12 months of follow-up. | — |
Secondary
| Measure | Time frame |
|---|---|
| The secondary efficacy outcomes included measures of physical performance, nutritional status, behavioral disturbance and depression. | — |
Countries
France
Outcome results
None listed