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The use of ß radiation as an adjunct to trabeculectomy in glaucoma

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN71955482
Enrollment
Unknown
Registered
2004-01-23
Start date
1993-01-04
Completion date
Unknown
Last updated
2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Eye diseases Eye Diseases Glaucoma

Interventions

It is proposed to use 750-1000 cGY of beta radiation to the eye following surgery. Patients will be randomised to receive an active or a dummy plaque and clinically followed up with measurements of in

Sponsors

NHS R&D Regional Programme Register - Department of Health (UK)
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients undergoing trabeculectomy

Exclusion criteria

Exclusion criteria: 'High-risk' glaucoma including juvenile glaucoma

Design outcomes

Primary

MeasureTime frame
Success defined as reduction in from baseline at peak drug effect, response rate and quality of life as measured using the Glaucoma disability index. I0P <21 mm Hg. 1. Completed = without medication 2. Qualified = with additional medication

Secondary

MeasureTime frame
Not provided at time of registration

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026