Comparison between laparoscopic complete mesocolic excision versus standard laparoscopic colonic resection for right-sided colon cancer

Feasibility and safety of laparoscopic complete mesocolic excision (CME) for right-sided colon cancer: a prospective clinical study

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN71842827

Enrollment

100

Registered

2020-04-07

Start date

2015-01-01

Completion date

Unknown

Last updated

2021-08-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Right-sided colon cancer Cancer Malignant neoplasm of colon

Interventions

Method of randomisation: cluster randomisation: CME group (cases): laparoscopic complete mesocolic excision and central vascular ligation NCME group (controls): standar

long-term follow-up in order to obtain results about oncological outcomes.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with right-sided colon cancer

Exclusion criteria

Exclusion criteria: Open surgery, right colon resections for inflammatory bowel diseases (IBD) and associated major surgical procedures

Design outcomes

Primary

Measure	Time frame
1. Operative time (skin-to-skin) in minutes, measured from medical records at the time of surgery 2. Intraoperative blood loss in mL, measured from medical records at the time of surgery 3. Other intraoperative complications: YES or NO and type of intraoperative complications (categorical variable), measured from medical records at the time of surgery 4. Conversion rate: YES or NO and percentage, measured from medical records at the time of surgery 5. Anastomotic leakage rate: YES or NO and percentage, measured from medical records during hospital stay 6. Specimen length: length in cm of surgical specimen, from histologic examination during 30 days 7. Lymph nodes harvesting: number of lymph nodes in surgical specimen, from histologic examination during 30 days	—

Measure

Time frame

1. Operative time (skin-to-skin) in minutes, measured from medical records at the time of surgery 2. Intraoperative blood loss in mL, measured from medical records at the time of surgery 3. Other intraoperative complications: YES or NO and type of intraoperative complications (categorical variable), measured from medical records at the time of surgery 4. Conversion rate: YES or NO and percentage, measured from medical records at the time of surgery 5. Anastomotic leakage rate: YES or NO and percentage, measured from medical records during hospital stay 6. Specimen length: length in cm of surgical specimen, from histologic examination during 30 days 7. Lymph nodes harvesting: number of lymph nodes in surgical specimen, from histologic examination during 30 days

—

Secondary

Measure	Time frame
Postoperative overall complications: YES or NO and type of postoperative complications (categorical variable), measured from medical records and radiologic imaging during hospital stay or 30 days	—

Countries

Italy

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026