Comparative effect of intraoperative propacetamol administration versus placebo on morphine consumption after elective reduction mammoplasty

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN71723173

Enrollment

Registered

2004-08-27

Start date

2000-03-01

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Morphine consumption and postoperative pain after intraoperative administration of placebo or propacetamol Surgery Pain, not elsewhere classified

Interventions

Intraoperative administration of propacetamol or placebo

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: 1. Informed consent adult women above 18 years 2. American Society of Anesthesiologists (ASA) I and II

Exclusion criteria

Exclusion criteria: 1. Preoperative use of analgesic drugs 2. Body mass index = 35 3. American Society of Anesthesiology physical status = 3 4. Sensitivity to paracetamol

Design outcomes

Primary

Measure	Time frame
Cumulative dose of morphine administered in the recovery room.	—

Secondary

Measure	Time frame
The secondary end-points were the pain score after tracheal extubation and one hour after, the delay for obtaining a Simplified Numerical Pain Scale (SNPS) less than 4, and the incidence of morphine side effects in the recovery room.	—

Countries

France

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026