Randomised controlled trial to compare the functional outcome of the standard NexGen Legacy knee replacement to that of the NexGen Legacy Flex knee replacement which is designed to allow a greater range of flexion in the knee

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN71676516

Enrollment

Registered

2006-12-04

Start date

2004-03-01

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Total knee replacement surgery in patients with osteoarthritis Surgery Osteoarthritis

Interventions

Standard NexGen Legacy knee replacement versus the NexGen Legacy Flex knee replacement

Eligibility

Inclusion criteria

Inclusion criteria: Patients with knee osteoarthritis who are on the waiting list to undergo unilateral total knee arthroplasty at the New Royal Infirmary in Edinburgh and who can passively flex their knee 90 degrees or more.

Exclusion criteria

Exclusion criteria: 1. Inflammatory polyarthritis 2. Disorders of the feet, hips or spine causing abnormal gait or significant pain 3. Dementia 4. Severe visual impairment 5. Neurological conditions affecting movement 6. Inability to give informed consent

Design outcomes

Primary

Measure	Time frame
Functional range of movement of the knee using flexible electrogoniometry	—

Secondary

Measure	Time frame
1. Passive range of motion 2. Pain 3. Knee extensor and flexor strength 4. Walking speed 5. Woman on the Move Against Cancer (WOMAC) 6. Knee Society Score 7. Daily Physical Activity 8. Quality of Life	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026