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Recurrence of chronic posttraumatic bone infection: Risk factors analysis

Predisposing factors for recurrence of chronic posttraumatic osteomyelitis: A retrospective observational cohort study from a tertiary referral center in Brazil.

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ISRCTN
Registry ID
ISRCTN71648577
Enrollment
150
Registered
2017-05-18
Start date
2007-08-01
Completion date
Unknown
Last updated
2017-11-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic post-traumatic osteomyelitis Musculoskeletal Diseases Chronic post-traumatic osteomyelitis

Interventions

This is a retrospective chart review study. The focus of the data collection is to compare characteristics of patients according to outcome, defined as treatment success and failure (recurrence) of PT

Sponsors

Fundação Faculdade de Medicina de São José do Rio Preto
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Older than 12 years of age 2. At least one year of follow-up after the surgical procedures 3. Diagnosed with chronic osteomyelitis 4. Complete medical records 5. Osteomyelitis was defined based upon the Center for Disease Control and Prevention (CDC)/National Healthcare Safety Network (NHSN) guidelines 6. Patients in remission of infection when there was absence of clinical, laboratory, or radiological signs of infection evaluated during the last medical visit (minimum of one year of follow-up), and in cases in which there was no need for reoperation or administration of an extra course of antibiotic therapy for the same site of infection following the end of therapy 7. Treatment failure or recurrent infection was defined as infection at the same site that had been previously controlled and required reoperation and/or a second complete course of parenteral antibiotic therapy

Exclusion criteria

Exclusion criteria: 1. Diagnosed with a previous history of infection at the same site 2. Incomplete medical records

Design outcomes

Primary

MeasureTime frame
Risk factors predisposing patients to recurrence of PTO (subjects, injury, pathogen, and surgery-associated) are measured using medical records within one year from diagnosis.

Secondary

MeasureTime frame
The frequency of recurrence following treatment of PTO is measured using medical records at first medical visit.

Countries

Brazil

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Mar 9, 2026