Influence of glucose degradation products on residual renal function in peritoneal dialysis (PD) patients

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN71335154

Enrollment

Registered

2006-03-23

Start date

1999-03-13

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

End-stage renal disease Urological and Genital Diseases Renal disease

Interventions

Conventional PD fluids with high amounts of glucose degradation products versus PD fluids with low amounts of glucose degradation products

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. End-stage renal disease 2. Treatment with PD 3. Age =18 years 4. Residual renal function =3 ml/min or creatinine clearance =6 ml/min 5. Negative serology for hepatitis B virus (HBV), hepatitis C virus (HCV), human immunodeficiency virus (HIV) 6. Written informed consent

Exclusion criteria

Exclusion criteria: 1. Pregnancy and lactation 2. Age >80 years 3. Multiple peritonitis episodes 4. Active malignancy

Design outcomes

Secondary

Measure	Time frame
1. Peritoneal membrane transport parameters 2. CA 125 in effluent as marker for mesothelial cell mass/viability 3. Records of routine blood analyses, hospitalisation, peritonitis episodes, blood pressure	—

Primary

Measure	Time frame
Time response of residual renal function	—

Countries

Germany

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026