Randomized Trial of Heat Recovery Ventilators (HRVs) for the Prevention of Severe Lower Respiratory Tract Infection (LRTI) in Inuit Infants in Baffin Region, Nunavut, Canada

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN71224182

Enrollment

150

Registered

2005-11-04

Start date

2005-09-15

Completion date

Unknown

Last updated

2019-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bronchiolitis, Pneumonia Respiratory Lower respiratory tract infection

Interventions

Heat Recovery Ventilator versus placebo Heat Recovery Ventilator

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Inuit infants 0-2 years of age living in eligible communities in Baffin Region, Nunavut, Canada

Exclusion criteria

Exclusion criteria: Children with underlying congenital malformations known to increase the risk of LRTI, including congenital lung malformations and congenital heart disease will be excluded from the study, as well as children with underlying conditions known to increase the risk of LRTI, including cystic fibrosis, severe developmental delay, and immunodeficiency. Houses where it is technically impossible to install the HRV will be excluded from the study. Only households providing informed consent will be allowed to participate in the trial.

Design outcomes

Primary

Measure	Time frame
Admission to hospital for severe lower respiratory tract infection	—

Secondary

Measure	Time frame
Effect of Heat Recovery Ventilators on indoor CO2, Air change rate, respiratory symptoms, occupant comfort, and visits to the nursing station for respiratory illness.	—

Countries

Canada

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026