Allergic disease, soil-transmitted helminths Skin and Connective Tissue Diseases Allergic disease
Conditions
Interventions
The original study protocol used three-monthly single dose Mebendazole 500 mg over one year. After the first treatment round, investigators noticed low efficacy of this regime. Therefore, a treatment
Sponsors
University of Nottingham (UK)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: All primary and secondary school children (age 6-15) in four communes in Khanh Hoa province, central Viet Nam
Exclusion criteria
Exclusion criteria: Known allergy to Albendazole
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in percent fall in peak expiratory flow after exercise challenge post gut worm treatment | — |
Secondary
| Measure | Time frame |
|---|---|
| Change in skin prick test hypersensitivity, host cytokine profiles, and allergic disease prevalence (skin examination for eczema and questionnaire-based for wheeze and rhinitis) post gut worm treatment | — |
Countries
Viet Nam
Outcome results
None listed