Postoperative pain after root canal filling using two different bio-ceramic sealers

Postoperative pain after root canal filling with different bio-ceramic endodontic sealers: a double-blind randomised clinical trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN70977847

Enrollment

Registered

2026-06-30

Start date

2025-03-15

Completion date

Unknown

Last updated

2026-07-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post root canal treatment pain Oral Health

Interventions

Non-surgical root canal treatment with two different types of tricalcium silicate sealers (TotalFill® BC Sealer or Bio-C)

Eligibility

Sex/Gender

All

Age

18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Willing to participate and provide informed con-sent 2. Required root canal treatment 3. Medically healthy (American Society of Anesthesiologists [ASA] Class I or II) 4. Aged 18 years or older 5. Normal periapical radiographic appearance or a periapical lesion <2 mm 6. Restorable tooth 7. Periodontally healthy tooth

Exclusion criteria

Exclusion criteria: 1. Under 18 years of age 2. Pregnant 3. Declined participation 4. Previously endodontically treated tooth 5. Tooth with an open apex 6. Presence of a deep isolated periodontal pocket 7. Tooth fracture 8. Root resorption 9. Endo-perio lesion 10. Non-restorable tooth 11. Tooth with mishaps

Design outcomes

Primary

Measure	Time frame
Postoperative pain measured using visual pain analogue scale at 7 days	—

Countries

Saudi Arabia

Contacts

Public ContactMohammed Alzahrani

m.sarhan@bu.edu.sa0543291242

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Jul 23, 2026