Randomised trial of human immunodeficiency virus (HIV)/sexually transmitted infection (STI) prevention in Zimbabwean youths

The Regai Dzive Shiri Project: a cluster randomised controlled trial to determine the effectiveness of a multi-component community-based human immunodeficiency virus (HIV) prevention intervention for rural youths in Zimbabwe

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN70775692

Enrollment

22000

Registered

2009-05-12

Start date

2003-03-31

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

HIV prevention and reproductive health Infections and Infestations Unspecified human immunodeficiency virus [HIV] disease

Interventions

The intervention is theoretically based in social learning theory and the stages of change model. It aims to achieve change in societal norms within communities. The intervention has three components:

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. For intervention: young people (aged 12 - 24 years, either sex) living in 15 early intervention implementation trial communities 2. For participation in final evaluation survey: all 18 - 22 year olds living in selected enumeration areas in trial communities

Exclusion criteria

Exclusion criteria: Does not meet inclusion criteria

Design outcomes

Primary

Measure	Time frame
1. HIV prevalence 2. HSV-2 prevalence Measured in 2007 after 4 years of intervention delivery.	—

Secondary

Measure	Time frame
1. Pregnancy 2. Reported sexual behaviour 3. Knowledge and attitudes related to HIV acquisition and reproductive health Measured in 2007 after 4 years of intervention delivery.	—

Countries

Zimbabwe

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026