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Wound closure following hip arthroplasty

Wound closure following hip arthroplasty: a multicentre randomised controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN70685656
Enrollment
219
Registered
2010-02-05
Start date
2010-04-05
Completion date
Unknown
Last updated
2017-04-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post-operative wound leakage and surgical site infection Surgery Infection following surgery

Interventions

All subjects in each of three randomised groups will have total hip arthroplasty wounds closed in layers with absorbable sutures. Subcuticular skin closure will be performed using monofilament suture

Sponsors

NHS Greater Glasgow and Clyde (UK)
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Anyone requiring elective Total Hip Replacement at Glasgow Royal Infirmary or Royal Alexandra Hospital (Paisley) 2. Able to give informed consent 3. Aged over 18 years, either sex

Exclusion criteria

Exclusion criteria: 1. Known glue allergy 2. Coagulation disorder 3. Unable to give informed consent

Design outcomes

Primary

MeasureTime frame
Wound leakage at 3 days post-operative

Secondary

MeasureTime frame
1. Wound complications including infection, assessed daily until patient is discharged and followed up at 3 months, and discharge, assessed daily until patient is discharged from hospital. Any discharge beyond day 4 will be classified as prolonged 2. Time to discharge 3. Cosmetic appearance, measured using a modified Hollander Scale to assess cosmesis at 3 months post-operatively 4. Pain, measured using a visual analogue scale to assess pain daily until discharge and at 3 months

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026