Does thumb joint mobilization decrease hyperalgesia in elderly patients with secondary thumb carpometacarpal osteoarthritis?

Hypoalgesic effects of glide mobilization on elderly patients with secondary thumb carpometacarpal osteoarthritis - a randomized, controlled trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN70578774

Enrollment

Registered

2011-05-26

Start date

2009-12-20

Completion date

Unknown

Last updated

2017-07-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thumb carpometacarpal osteoarthritis (TCOA) Musculoskeletal Diseases Osteoarthritis

Interventions

1. Glide mobilization 1.1. We performed a glide mobilization also known as mobilization of posterior-anterior gliding of the TMJ, taking into account the convex/concave rule 1.2. The direction of dec

the action is repeated three times 1.8. The physiotherapist glides the first metacarpal bone in a posterior-anterior orientation 1.9. In the posterior-anterior gliding movement of the first metacarpal

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients who used the dominant hand systematically such as ex-factory workers and home workers 2. Diagnosed with secondary thumb carpometacarpal osteoarthritis (TCOA) in the dominant hand by X-ray detection of stage III and IV according to the Eaton-Littler-Burton Classification 3. The population of the study was 70-90 years old and were male and females

Exclusion criteria

Exclusion criteria: 1. Patients with a medical history of carpal tunnel syndrome, arthritis, surgical interventions on CMC joint, or D?Quervain?s tenosynovitis 2. Patients presenting degenerative or non-degenerative neurological conditions in which pain perception was altered

Design outcomes

Primary

Measure	Time frame
1. Pain measurement 1.1. The pressure pain threshold (PPT) was measured by using a mechanical pressure algometer (Wagner Instruments, Greenwich, CT, USA) with a 1cm2 rubber-tipped plunger mounted on a force transducer 1.2. The PPT is defined as the minimum amount of pressure that results in the sense of pressure changing to pain 1.3. The mean of three measurements (intra-examiner reliability) was calculated and used for the main analysis 1.4. The range of values of the pressure algometer was 0 to 10 kg, with a minimal sensibility of 0.1 kg 1.5. For these specific cases, the algometry has higher reliability (Intra-class correlation coefficient [ICC]=0.91, Interval confidence [IC] del 95%: 0.82-0.97) for PPT measurement in older patients 1.6. In addition, previous studies have reported an intra-examiner reliability for this procedure ranging from 0.6 to 0.97, and the inter-examiner reliability ranged from 0.4 to 0.98 1.7. PPT measurements were collected at both thecarpometacarpal (CMC) joint at the bottom of the anatomical snuffbox and tubercle of the scaphoid bone 2. Strength measurements 3. Pinch strength 3.1 The pinch strength was measured by a mechanical pinch gauge (Baseline, NY, USA) while the patient was in the sitting position with the shoulder adducted and neutrally rotated and the elbow flexed at 90° 3.2. Two different measurements were taken: first, the tip pinch between the index finger and thumb and, then, the tripod pinch between the index and medial fingers and the thumb 3.3. The reliability of this procedure to measure the pinch strength has been found to be on the order of 0.93 4. Grip strength measurements 4.1. Grip strength measurements were taken with a grip dynamometer (Baseline, NY, USA) while the patient was also in the sitting position, which has a precision and reliability of ± 3% for grip strength measurements 4.2. The reliability of the measurements was expressed by ICC between 0.82 and 0.97 for grip strength measurements 5. Pinch streng	—

Measure

Time frame

1. Pain measurement 1.1. The pressure pain threshold (PPT) was measured by using a mechanical pressure algometer (Wagner Instruments, Greenwich, CT, USA) with a 1cm2 rubber-tipped plunger mounted on a force transducer 1.2. The PPT is defined as the minimum amount of pressure that results in the sense of pressure changing to pain 1.3. The mean of three measurements (intra-examiner reliability) was calculated and used for the main analysis 1.4. The range of values of the pressure algometer was 0 to 10 kg, with a minimal sensibility of 0.1 kg 1.5. For these specific cases, the algometry has higher reliability (Intra-class correlation coefficient [ICC]=0.91, Interval confidence [IC] del 95%: 0.82-0.97) for PPT measurement in older patients 1.6. In addition, previous studies have reported an intra-examiner reliability for this procedure ranging from 0.6 to 0.97, and the inter-examiner reliability ranged from 0.4 to 0.98 1.7. PPT measurements were collected at both thecarpometacarpal (CMC) joint at the bottom of the anatomical snuffbox and tubercle of the scaphoid bone 2. Strength measurements 3. Pinch strength 3.1 The pinch strength was measured by a mechanical pinch gauge (Baseline, NY, USA) while the patient was in the sitting position with the shoulder adducted and neutrally rotated and the elbow flexed at 90° 3.2. Two different measurements were taken: first, the tip pinch between the index finger and thumb and, then, the tripod pinch between the index and medial fingers and the thumb 3.3. The reliability of this procedure to measure the pinch strength has been found to be on the order of 0.93 4. Grip strength measurements 4.1. Grip strength measurements were taken with a grip dynamometer (Baseline, NY, USA) while the patient was also in the sitting position, which has a precision and reliability of ± 3% for grip strength measurements 4.2. The reliability of the measurements was expressed by ICC between 0.82 and 0.97 for grip strength measurements 5. Pinch streng

—

Secondary

Measure	Time frame
No secondary outcome measures	—

Countries

Italy

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026