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CORPUS 1 pilot study: evaluating the impact of physical capacity on the quality of single operator continuous-chest-compression-only cardio pulmonary resuscitation

An observational pilot study to evaluate the impact of physical capacity on the quality of single operator continuous-chest-compression-only cardio pulmonary resuscitation

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ISRCTN
Registry ID
ISRCTN70447230
Enrollment
15
Registered
2010-02-09
Start date
2009-07-01
Completion date
Unknown
Last updated
2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Critical cardiac care Circulatory System Cardiac care

Interventions

Each subject was instructed to perform sustained, single operator, chest-compression-only cardiocerebral resuscitation (CCR) up to 15 minutes or until exhaustion when the 15-minute CCR session could n
CCR quality is defined as the number of compressions with adequate depth within a certain timeframe (expressed as %).

Sponsors

Heart Centre Hasselt vzw (Belgium)
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Active healthcare professionals (12 intensive cardiac care nurses, 3 physicians) 2. Between the ages 18 and 65 years, either sex 3. Working at the Jessa Hospital, Hasselt, Belgium 4. Subjects were required to be able to achieve a maximal voluntary cardiopulmonary exercise test

Exclusion criteria

Exclusion criteria: Any chronic disease

Design outcomes

Primary

MeasureTime frame
1. Average values of compression rate (ECCs/min) and compression depth (mm), obtained after 1 minute, 3 minutes, and for two consecutive time periods of 5 minutes (5 - 10?, 10 - 15?) 2. Heart rate during CCR, measured continuously by using a commercial heart rate monitor (Polar, Oy, Finland) 3. Blood lactate levels (mmol/L), measured with capillary blood samples taken at baseline and after 5, 10 and 15 minutes and using an automated lactate analyser

Secondary

MeasureTime frame
1. Cardiopulmonary exercise capacity. All subjects performed a maximal cardiopulmonary bicycle exercise test, designed to reach peak oxygen uptake capacity (VO2peak) within 8 - 12 minutes, as executed in previous studies from our laboratory. During the cycling test, an electronically braked Ergo 1500 cycle (ErgoFit, Pirmasens, Germany) was used. The cycling frequency was set at 70 cycles/min and the test was ended when the subject failed to maintain a cycling frequency of at least 60 cycles/min. Both the starting and incremental cycling resistance was set between 30 and 45 Watts, depending on age, height, weight, and gender. The cycling resistance increased every single minute. Before every test, a gas and volume calibration was done automatically. During the tests, environmental temperature was kept stable (20°C). During the exercise tests, pulmonary gas exchange analysis was performed by a cardiopulmonary ergospirometry device (Schiller CS200, Schiller AG, Switzerland). Oxygen uptake capacity (VO2), respiratory exchange ratio (RER), and carbon dioxide output (VCO2) were collected breath-by-breath and averaged every 10 seconds. By plotting exercise VO2 against exercise VCO2, ventilatory threshold was calculated by V-slope method, as executed in previous studies from our laboratory. A software programme of the ergospirometry device determined the break point of the two slopes. Maximal cycling power output (Wpeak) was reported. 2. Muscle strength. Muscle strength measurements of the upper body were performed using a standardised strength testing protocol on an isokinetic dynamometer (Biodex). Following a 5-minute standardised warming-up (Technogym Lat Pull, Pectoral, ArmCurl), subjects were positioned and fixated in a semi supine (15° backward inclination) sitting position (shoulder and thorax fixation). The rotational axis of the dynamometer was aligned with the transverse shoulder/elbow-joint axis and strapped to the distal end of the humerus/radius-ulna. The align

Countries

Belgium

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Mar 27, 2026