Early restorative crown therapy in children and adolescents with amelogenesis imperfecta

Early restorative crown therapy in children and adolescents with amelogenesis imperfecta: a prospective double-blind randomised controlled trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN70438627

Enrollment

Registered

2012-01-26

Start date

2009-01-01

Completion date

Unknown

Last updated

2016-11-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Amelogenesis imperfecta Oral Health Disturbances in tooth formation

Interventions

Treatment with Procera crown therapy with zirkonia inner couping cemented with Rely X ARC cement or E-MAX crowns with zirkonia inner couping cemented with Rely X ARC in children and adolescents with a

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Children and adolescents with amelogenesis imperfecta, 6 to 25 years of age, referred for oral rehabilitation

Exclusion criteria

Exclusion criteria: Amelogenesis imperfecta in combination with syndromes including mental retardation

Design outcomes

Primary

Measure	Time frame
1. Quality of restorations after 1 month, 1 year and a 2-year observation period according to Ryge & De Vinzenci (1983) 2. Sensitivity, measured using the Visual Analogue Scale (VAS) score (0 = no pain, 10 = unbearable pain) at baseline, 1 month and 2 years	—

Secondary

Measure	Time frame
1. Dental caries according to Amarante et al (1998) 2. Gingivitis and periodontitis according to Nyman and Linde (2003) 3. Apical status according to Örstavik (1986)	—

Countries

Sweden

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Mar 5, 2026