Postoperative pain after root canal treatment Oral Health
Conditions
Interventions
Patients are randomised to one of two groups.
Group 1: Patients receive 1.8 mL of 2% lidocaine with clonidine (15 µg/mL) using a conventional inferior alveolar nerve block (IANB).
Sponsors
Isfahan University of Medical Sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Adult patients (18 years of age or older) 2. In good medical condition (American Society of Anesthesiologists classification 1) 3. Diagnosed with symptomatic irreversible pulpitis and normal/symptomatic apical periodontitis at the mandibular first or second molars
Exclusion criteria
Exclusion criteria: 1. Patients with active signs of oral infections or inflammation 2. History of addiction or use of ß blockers 3. Patients taking any medications that could affect anesthetic assessment (analgesics or opioids at least one week before treatments) 4. Patients with allergies or contraindications to the use of clonidine, epinephrine or ibuprofen 5. Female patients who were pregnant or breastfeeding 6. Patients with no response to cold testing 7. Perirapical pathosis (other than a widened periodontal ligament) 8. No vital coronal pulp tissue upon access cavity preparation (partial necrosis)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Pain scores, recorded using a Heft-Parker visual analog scale (VAS) preoperatively and at 6, 12, 24, 36, 48, and 72 hours after endodontic treatment 2. Number of pain medications consumed are recorded continuously for 72 hours postoperatively | — |
Secondary
| Measure | Time frame |
|---|---|
| Duration of postoperative pain is assessed using a visual analog scale (VAS) preoperatively and at 6, 12, 24, 36, 48, and 72 hours | — |
Countries
Iran
Outcome results
None listed