The effects of transcranial direct current stimulation on the brain electrical signal changes that happen to nicotine users: an exploratory study

The effects of transcranial direct current stimulation on EEG changes in nicotine use disorder patients: an exploratory study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN70382365

Enrollment

Registered

2024-06-26

Start date

2024-10-01

Completion date

Unknown

Last updated

2025-01-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nicotine use disorder Mental and Behavioural Disorders

Interventions

Transcranial Direct Current Stimulation (tDCS). Participants will receive tDCS intervention lasting 20 minutes per session. These sessions will occur 5 days a week, spanning 2 weeks. The tDCS will be

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Aged 18-55 years 2. Diagnosed with nicotine use disorder as defined by the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) 3. Healthy with no history of seizure, epilepsy, head trauma, or head surgery

Exclusion criteria

Exclusion criteria: 1. Concomitant psychiatric disorder 2. Polysubstance disorder/uses 3. On psychotropic treatment

Design outcomes

Primary

Measure	Time frame
EEG is measured using the standard 64-channel EEG machine at baseline (T0), week 1 (T1) and week 6 (T6)	—

Secondary

Measure	Time frame
1. Nicotine dependence assessed using the Fagerstrom Test for Nicotine Dependence (FTND) at baseline (T0), week 1 (T1) and week 6 (T6) 2. Withdrawal symptoms assessed using the Minnesota Nicotine Withdrawal Scale (MNWS) at baseline (T0), week 1 (T1) and week 6 (T6)	—

Countries

Malaysia

Contacts

Public ContactYee Hway Ann @ Anne Yee Yee

anne.yee@monash.edu+60 (0)198891360

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026