Intubation Surgery
Conditions
Interventions
Patients will be extubated initially into 30% FiO2, and their SpO2 recorded when stable for scoring purposes. Higher or lower FiO2 can then be given if needed. Patients will be entered into the study
2. At the moment that stridor is first recognised
3. One minute after randomisation
4. Every thirty minutes after randomisation, until the trial ends
and
5. At the end of any dose of nebulised adrenaline
Any patient with a modified Syracuse score of 3 or more at points 3, 4 or 5 will receive nebulised adrenaline 1:1000 0.5ml/kg (maximum single d
if not, no further dose will be given until the next score (30 minutes after the last, pre-nebuliser score). A modified Syracuse score of 3 or more persisting after three continuous adrenaline nebulis
Sponsors
Department of Health (UK)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: All children intubated are eligible for the trial. Parents will be approached and consented at the appropriate time (prior to planned extubation).
Exclusion criteria
Exclusion criteria: Patients with undrained pneumothoraces or intracranial air will be excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Stridor scores analysed by Student's t-test 2. Adrenaline use (directly linked to stridor scores) analysed by Student's t-test 3. Re-intubation rates analysed by Chi-squared test | — |
Secondary
| Measure | Time frame |
|---|---|
| Not provided at time of registration | — |
Countries
United Kingdom
Outcome results
None listed