Efficacy of different over-the-counter analgesics for postoperative pain following oral biopsy

Efficacy of different over-the-counter analgesics for postoperative pain following oral biopsy: a quasi-experimental study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN70034520

Enrollment

Registered

2025-09-26

Start date

2018-04-30

Completion date

Unknown

Last updated

2025-10-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative pain following oral mucosal biopsy Oral Health

Interventions

Patients will receive the following treatment for postoperative pain following oral mucosal biopsy: Group A: Acetaminophen 1000 mg every 6 hours Group B: Ibuprofen 600 mg every 6 hours Group C: Combin

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Adults (18–90 years) 2. Scheduled for oral biopsy at KAU-FD 3. Capacity to judge pain

Exclusion criteria

Exclusion criteria: 1. Patients with pain at baseline 2. Currently on pain or mood-altering medications 3. Allergic to any of the medications

Design outcomes

Primary

Measure	Time frame
Postoperative pain intensity measured using a Visual Analog Scale (VAS, 0–10) at 4, 24, and 48 hours after the biopsy procedure	—

Secondary

Measure	Time frame
Incidence of medication side effects or adverse events measured using data collected in Case Report Forms during the 72-hour treatment period	—

Countries

Saudi Arabia

Contacts

Public ContactSara Akeel

sakeel@kau.edu.sa+966126952000

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026