Postoperative nausea, vomiting and constipation in patients undergoing knee replacement Surgery
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients aged 18 to 75 years who need knee replacement due to end-stage osteoarthritis 2. Patients who voluntarily participate in clinical trials and sign informed consent forms with good compliance
Exclusion criteria
Exclusion criteria: 1. Patients undergoing revision and bilateral joint replacement 2. Patients who have received acupuncture treatment within 2 weeks 3. Patients with rheumatoid disease, systemic lupus erythematosus and ankylosing spondylitis 4. Patients with severe deformity of knee joint (knee flexion =30 degrees, varus =30 degrees or valgus =15 degrees) 5. severe hepatic and renal insufficiency 6. Patients with central nervous system or mental illness 7. Those who are experiencing nausea, vomiting, diarrhea or constipation, and those who are taking drugs or non-drugs to treat nausea, vomiting, diarrhea or constipation, and those who are taking drugs that affect gastrointestinal motility 8. Skin allergy, breakage, infection or itching at the test site, etc
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of PONV measured using questionnaire at 3, 6, 12 and 24 hours after the operation | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. The severity of nausea and vomiting measured using questionnaire in the 24 hours after the operation 2. First exhaust time and defecation time after the operation, measured using questionnaire 3. Levels of hemoglobin, albumin and electrolyte in blood measured using hospital monitoring system after the operation 4. The incidence of constipation measured using questionnaire at 3 days after the operation 5. Stratified analysis on the basis of anesthesia method and the risk of nausea and vomiting | — |
Countries
China